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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
supplement:
Glucose
Research Papers that Mention the Interaction
“It also acts as a potent antioxidant and regulates glucose and lipid metabolism, although the exact action mechanism is not clear.”
Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha‐2‐HS‐glycoprotein“This study demonstrates that high glucose induces an increase in antioxidant enzyme levels in human endothelial cells, suggesting that elevated glucose levels may produce an oxidative stress in the cells.”
“It has been found that antioxidant agents reduce the effect of glucose , confirming the involvement of reactive oxygen species (ROS) in the effect of glucose.”
“The antioxidants inhibited the dextrose induced SO production while in high concentrations they aggravated ER stress.”
“Increased antioxidant defensive responses were evidenced by increased antioxidant enzymes expression and decreased superoxide production after glucose reduction.”
“Consistently, abrogation of this mitochondrial ROS signal by antioxidants impairs the lifespan-extending and health-promoting capabilities of glucose restriction and physical exercise, respectively.”
“Whereas no correlation was found between FR and any of the routine clinical parameters tested, a negative correlation was observed between AtxGap and glucose content (p=0.025) and between AtxGap and γ-glutamyltransferase (p=0.05).”
“The increased baseline fluorescence suggests that the antioxidant pool may be depleted within the first hour of exposure to high concentrations of dextrose.”
“In vitro experiments showed that high glucose induced the accumulation of reactive oxygen species and activated NLRP3 inflammasomes, which was significantly suppressed by treatment with metformin or antioxidant N-acetyl-L-cysteine.”
Metformin inhibited Nod-like receptor protein 3 inflammasomes activation and suppressed diabetes-accelerated atherosclerosis in apoE-/- mice.“Phenotypically normal mice heterozygous for the Aqp11 mutation repeatedly treated with glucose showed increased blood urea nitrogen levels that were prevented by the antioxidant sulforaphane or by phlorizin.”
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