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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Antioxidants and Galactose





Research Papers that Mention the Interaction

Our results show significant weakened antioxidant defense in HLEC when incubated in the presence of galactose as compared to normal.
Molecular and Cellular Biochemistry  •  2002  |  View Paper
It significantly elevated the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and total antioxidant capacity T-AOC ), which were suppressed by D-galactose.
Biomedical and environmental sciences : BES  •  2017  |  View Paper
Our findings lend support to a potential therapeutic strategy for this disease, which may include the use of antioxidants for ameliorating the damage caused by galactose.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2017  |  View Paper
Data showed that at the pathologically high concentration (greater than 5.0 mM), galactose induces lipid peroxidation, protein carbonylation, alters antioxidant defenses in the cerebrum, and also alters cholinesterase activity.
Metabolic Brain Disease  •  2016  |  View Paper
Further results showed that Forkhead box O3a (FOXO3a), … 2-related factor 2 (Nrf2), and their targeted antioxidants such as superoxide dismutase 2 (SOD2), catalase (CAT), glutathione reductase (GR), glutathione (GSH), glutamate-cysteine … heme oxygenase 1 (HO-1) were all inhibited in the aging rats induced by D-galactose treatment.
Oxidative medicine and cellular longevity  •  2014  |  View Paper
A. CONCLUSIONS (a) Gal and its derivatives may produce free radicals in the suckling rat brain, reported for first time, (b) Na+,K+ -ATPase … play a protective role reversing the inhibited Na+,K+ -ATPase toward normal in in vitro galactosaemia and (d) the addition of the above antioxidants … Gal ….
Pharmacological research  •  2004  |  View Paper