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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Antioxidants and Fenretinide



Research Papers that Mention the Interaction

Such an inhibitory effect of 4HPR was abolished by antioxidants and by inhibitors of 12-lipoxygenase, baicalein (specific) and esculetin (panspecific).
Free radical biology & medicine  •  2005  |  View Paper
All these 4HPR's effects, as well as the induction of apoptosis, were inhibited by antioxidants , which decrease ROS.
Oncogene  •  1999  |  View Paper
We found that 4HPR induced apoptosis in all of the cell lines; however, this effect was blocked by antioxidants in only 2 of the 10 cell lines.
Cancer research  •  1999  |  View Paper
In this study we show that addition of antioxidants to HL-60 cells cultured in the presence of 3 microM HPR , markedly suppresses the apoptopic effect of the retinoid and significantly prolongs cell survival (48-96 h).
Carcinogenesis  •  1997  |  View Paper