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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
drug:
Febuxostat
Research Papers that Mention the Interaction
“Indeed, febuxostat , a novel xanthine oxidase inhibitor, has been reported to decrease not only oxidative stress levels (derivatives of reactive oxygen metabolites) but also antioxidant potential (biological antioxidant potential) in hyperuricemia patients.”
Is Serum Uric Acid a Biomarker, but not a Mediator in Patients With Lifestyle and Cardiovascular Diseases?“ Febuxostat also displayed a potent anti-inflammatory and antioxidant activity by decreasing serum levels of lipid peroxidation index, proinflammatory cytokines, and enhancing antioxidant enzyme activity.”
Effect of febuxostat on biochemical parameters of hyperlipidemia induced by a high-fat diet in rabbits.“The present study suggests that antioxidant , anti-inflammatory, and cytoprotective mechanisms potentially mediate the renoprotective effects of febuxostat in CIS-administered rats, presenting febuxostat as a promising combinatorial strategy for cancer patients undergoing CIS chemotherapy.”
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