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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Antioxidants and Fasudil





Research Papers that Mention the Interaction

The results showed that fasudil significantly suppressed ROCK activity, potently elevated the activities of antioxidant enzymes and the expression of endothelial nitric oxide synthase, as well as the concentration of nitric oxide in the serum and cardiac tissue.
Clinical and experimental pharmacology & physiology  •  2011  |  View Paper
Fasudil significantly reduced the abundances of the Rho A, ROCK 1, and ROCK 2 proteins, restored the activities of … oxidase (MAO) in cardiac mitochondria, inhibited the opening of the mitochondrial permeability transition pore, and decreased the total antioxidant capacity, as well as levels of …, and superoxide dismutase in heart.
BioMed research international  •  2013  |  View Paper