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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
supplement:
Diallyl Disulfide
Research Papers that Mention the Interaction
“The results indicate that DAS augments antioxidant defense with anti-inflammatory response against HgCl2-induced neurotoxicity.”
Pretreatment with diallylsulphide modulates mercury-induced neurotoxicity in male rats.“In contrast, DADS prevented the depletion of cytoplasmic Nrf2 and enhanced nuclear translocation of Nrf2, which, in turn, upregulated antioxidant and/or phase II enzymes.”
“These findings indicate that DADS induces antioxidant defense mechanism by activating Nrf2 pathway and reduces inflammatory response by inhibiting NF-κB activation.”
“ DADS also reduced the expression of proinflammatory proteins including inducible nitric oxide synthase (iNOS), nuclear factor (NF)-κB, and matrix metalloproteinase (MMP)-9, and it enhanced the expression of antioxidant proteins including Nrf-2 and hemeoxygenase (HO)-1.”
“ DADS caused a decrease in the activity of all antioxidant enzymes except catalase, resulting in oxidative stress and damaged cells.”
Effect of diallyldisulphide on an antioxidant enzyme system in Candida species.“Oral treatment of diallyl disulphide DADS ) results in the resynchronization of the altered rhythms of TBARS and other antioxidants.”
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