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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Antioxidants
drug:
Dexmedetomidine
Research Papers that Mention the Interaction
“In summary, cotreatments with Dex and Na2SeO3 further improved antioxidant and anti-inflammatory protection of myocardial cells from I/R injury compared to their individual treatments.”
Cotreatments with Dex and Na2SeO3 further improved antioxidant and anti-inflammatory protection of myocardial cells from I/R injury compared to their individual treatments“CONCLUSIONS De medetomidine pr eserves the ant ioxidant en zyme levels and reduces toxic oxidant metabolites.”
Dexmedetomidine acts as an oxidative damage prophylactic in rats exposed to ionizing radiation.“In conclusion, pretreatment with Dex activates Nrf2 through α 2A receptor, increases the antioxidant levels, and attenuates renal injury during OALT.”
“Analyzing the antioxidant effects of increasing doses … Dex in torsion and contrlateral testicles: Dex 100 µg/kg statistically significant … the tissue total antioxidant status ( TAS ) and oxidative stress index (OSI) when compared with Dex 50 µg/kg but not found significantly change on the tissue total oxidant status (TOS).”
“RESULTS Increasing doses of De si gnificantly increased TAS , a nd significantly decreased OSI.”
“Therefore, oxidant/antioxidant parameters play a role in the antiulcer mechanism of dexmedetomidine.”
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