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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Antioxidants and Cysteine

supplement:

Antioxidants

supplement:

Cysteine

Research Papers that Mention the Interaction

Recent work has shown supplementation with a cysteine donor (N-acetylcysteine; NAC) improves antioxidant capacity by augmenting glutathione levels and reducing markers of oxidative stress, as well as ergogenic potential through association with delayed fatigue in numerous experimental models.
Journal of the International Society of Sports Nutrition  •  2017  |  View Paper
Also, mean E(h) Cys was significantly more reduced in the antioxidant group (-74 vs -67.3 mV, P = .03).
American journal of ophthalmology  •  2005  |  View Paper
Cysteine , N-acetyl cysteine and glutathione significantly reduced the radical intensity and cytotoxic activity of these antioxidants except for sodium 5,6-benzylidene-L-ascorbate.
Anticancer research  •  1997  |  View Paper
It is proposed that ascorbate and cysteine prevent the induction of non-specific suppressor activity in MNL by an anti-oxidant mechanism.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition  •  1983  |  View Paper
Moreover, increased brain Na+,K+-ATPase activity could be a marker of T deficiency in WE, while combined T and antioxidant co-supplementation of Cys and/or Carn could be neuroprotective in terms of restoring the examined crucial brain enzyme activities to control levels.
Metabolic Brain Disease  •  2013  |  View Paper
Rats treated with Ni exhibited a significant reduction in brain TAS (-47%, p < 0.001, BvsA) that was efficiently limited by the co-administration of Cys (-4%, p > 0.05, DvsA; +83%, p < 0.001, DvsB), while Cys (group C) had no effect on TAS.
Biological Trace Element Research  •  2011  |  View Paper
B resulted in a decrease of TAS to 30% (P < 0.01), while the presence of Cys or GSH increased TAS to 20% (P < 0.01) and 60% ( P < 0.001), respectively.
Pharmacological research  •  2004  |  View Paper
Taken together, these data suggest that supplementation with l-cysteine significantly reduced lipid peroxidation and ROS levels, but increased antioxidant levels and the mRNA and protein expression of MAP2 in rats following TBI.
3 Biotech  •  2019  |  View Paper
Dauphinee et al. discovered that growing A. madagascariensis in the presence of the antioxidants acetic acid and cysteine greatly reduced the number of holes that formed in its leaves and that the presence of holes was somewhat recovered by the further addition of hydrogen peroxide to the growth medium.
Nature Plants  •  2017  |  View Paper
Additionally, pre-treatment with the thiol antioxidant cysteine decreased both ROS production and reversed the changes in the miRNA signature in response to irradiation.
Front. Oncol.  •  2014  |  View Paper
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