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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Antioxidants
supplement:
Cuprous
Research Papers that Mention the Interaction
“Although apparently in contrast with the common view that Cu(I) and not Cu(II) is the … of LDL oxidation in the copper model, the results reported here indicate that the availability of Cu(I) during the initiation phase of … by copper antagonizes both antioxidant consumption and … extensive oxidation.”
“Furthermore, the direct addition of Cu(I) , together with Cu(II), to a suspension of isolated LDL efficiently delayed the onset of extensive lipid peroxidation and decreased the rate of antioxidant consumption.”
“Moreover, the initial rate of Cu(II)-induced consumption of either endogenous antioxidants in LDL or free alpha-tocopherol in suspension was increased in the presence of BC, thus indicating that the continuous removal of Cu(I) enhanced both antioxidant consumption and LDL oxidation promoted by copper.”
Cu(I) availability paradoxically antagonizes antioxidant consumption and lipid peroxidation during the initiation phase of copper-induced LDL oxidation.
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