Possible Interaction: Antioxidants and Creatine

“In this case, the use of antioxidant supplements such as creatine can have positive effects on the antioxidant system.”

“Some studies have shown that creatine (Cr) protects tissues from ischemic damage by its antioxidant action.”

“Background Multiple studies suggest creatine mediates anti-oxidant activity in addition to its established role in cellular energy metabolism.”

“The observed significant increase in uric acid and the decrease in TAS suggest that creatine supplementation, despite promoting acute effects on muscle strength improvement, might induce oxidative stress and decreases total antioxidant status of subjects.”