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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
drug:
Ciprofloxacin
Research Papers that Mention the Interaction
“After accumulated in plant tissues, CIP significantly inhibited the plant growth, decreased the photosynthetic pigments contents and enhanced the antioxidant enzyme activities in a concentration-dependent manner.”
Chemical speciation of ciprofloxacin in aqueous solution regulates its phytotoxicity and uptake by rice (Oryza sativa L.).“At a dose of 10 mg/kg, CIP altered antioxidant enzymes and gene expression, but was not harmful to the growth and reproduction of E. fetida.”
“The antioxidant enzymes superoxide dismutase (SOD), peroxidase (POD), and glutathione (GSH) were inhibited after 10 mg/kg CIP exposure on day 21, and catalase (CAT) activity increased significantly on day 14.”
Effects of ciprofloxacin exposure on the earthworm Eisenia fetida.“These results suggest that hatching, early ontogeny, occurrence of morphological anomalies, antioxidant and biotransformation enzyme activity, and lipid peroxidation in fish can be affected by ciprofloxacin.”
“ Ciprofloxacin altered the prooxidant-antioxidant balance , with a decrease of oxidant metabolites and an increase of superoxide dismutase and catalase activity, being associated with high-levels of Stx production.”
“Furthermore, the treated groups with PTZ and CFX caused a decrease in aspartate, glutamate and total antioxidant capacity levels, while the concentrations of GABA and glycine were increased after 14 days.”
“Drugs with strong antioxidant such as tempol, melatonin and pentoxifylline might interfere with the antibacterial activity of ciprofloxacin.”
Ciprofloxacin-Induced Antibacterial Activity Is Atteneuated by Pretreatment with Antioxidant Agents“In summary, these results indicate that ciprofloxacin can induce resistance by the enhancement of antioxidant defense in planktonic bacteria, similar to the natural resistance occurring in biofilm.”
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