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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
drug:
Chlorpromazine
Research Papers that Mention the Interaction
“Chronic haloperidol or chlorpromazine but not clozapine treated rats showed decreased forebrain levels of antioxidant defence enzymes, superoxide dismutase (SOD) and catalase.”
Carvedilol attenuates neuroleptic‐induced orofacial dyskinesia: possible antioxidant mechanisms“ Chlorpromazine , thus, had a somewhat different action on antioxidant enzymes in different subcellular fractions.”
“The data indicate that chlorpromazine inhibition of lipid peroxidation and of accumulation of lipofuscin can result from elevation of the activity of brain antioxidant enzymes.”
“The inhibitory effect of CPZ was antagonized by the antioxidant N-acetyl L-cysteine and is likely caused by the parent compound.”
Short communication: Chlorpromazine causes a time-dependent decrease of lipids in Saccharomyces cerevisiae
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