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“The demonstrated cytotoxicity of CGA (1 mmol/L) and its inhibition of the antioxidant enzymes suggests the usefulness of phenolic compounds as a supporting pharmacological treatment for melanoma.”
“ CA alleviated ROS production and prevented the reduction of antioxidant capacity in cells exposed to PQ by increasing NF-E2-related factor 2 (Nrf2), superoxide dismutase 2 (SOD2) and glutathione levels.”
“Additionally, DCEQA upregulated the mRNA and protein expression of antioxidant enzymes superoxide dismutase‑1 and heme oxygenase‑1 which were inhibited under UVB irradiation.”
“The antioxidant protection, evaluated through the ratio GSH/GSSG, was significantly increased by chlorogenic acid in inflamed skin (P < 0.0001) and kidney (100 mg/day, P < 0.01; 150 mg/day, P < 0.0001).”
“Our findings suggested that CGA possessed dual-modulatory effects on antioxidant capacity of L. vannamei and could be a potential feed additive that can enhance shrimp resistance against environmental stresses.”
“Our previous studies have shown that chlorogenic acid CGA ) could significantly improve acute and chronic liver injury through antioxidant and anti-inflammatory activities.”
“The isoquercitrin, chlorogenic acid , and rutin contents of the free phenolic extracts displayed significant correlations with the antioxidant activities , while syringic acid and rutin were the main contributors to the antioxidant activities of the bound phenolic fractions.”