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Last Updated: 2 years ago

Possible Interaction: Antioxidants and Chlorogenic Acid

Research Papers that Mention the Interaction

The demonstrated cytotoxicity of CGA (1 mmol/L) and its inhibition of the antioxidant enzymes suggests the usefulness of phenolic compounds as a supporting pharmacological treatment for melanoma.
Journal of food biochemistry  •  2020  |  View Paper
CA alleviated ROS production and prevented the reduction of antioxidant capacity in cells exposed to PQ by increasing NF-E2-related factor 2 (Nrf2), superoxide dismutase 2 (SOD2) and glutathione levels.
Free radical research  •  2019  |  View Paper
Additionally, DCEQA upregulated the mRNA and protein expression of antioxidant enzymes superoxide dismutase‑1 and heme oxygenase‑1 which were inhibited under UVB irradiation.
Molecular medicine reports  •  2019  |  View Paper
The antioxidant protection, evaluated through the ratio GSH/GSSG, was significantly increased by chlorogenic acid in inflamed skin (P < 0.0001) and kidney (100 mg/day, P < 0.01; 150 mg/day, P < 0.0001).
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society  •  2020  |  View Paper
Additionally, pretreated CGA enhanced antioxidant enzymes and anti-inflammatory cytokines and, in contrast, attenuated oxidative stress and pro-inflammatory cytokine expression.
Molecules  •  2020  |  View Paper
However, whether the anti-oxidant activity is involved in the anti-fibrotic effect of CGA on liver fibrosis is not yet fully understood.
Clinical nutrition  •  2016  |  View Paper
Antioxidant activities showed significant association with phenolic compounds, such as caffeoylquinic acids , ferulic acid-O-hexosides and rutin.
Food chemistry  •  2016  |  View Paper
Our findings suggested that CGA possessed dual-modulatory effects on antioxidant capacity of L. vannamei and could be a potential feed additive that can enhance shrimp resistance against environmental stresses.
Fish & shellfish immunology  •  2015  |  View Paper
Our previous studies have shown that chlorogenic acid CGA ) could significantly improve acute and chronic liver injury through antioxidant and anti-inflammatory activities.
Frontiers in Pharmacology  •  2021  |  View Paper
The isoquercitrin, chlorogenic acid , and rutin contents of the free phenolic extracts displayed significant correlations with the antioxidant activities , while syringic acid and rutin were the main contributors to the antioxidant activities of the bound phenolic fractions.
BMC Chemistry  •  2021  |  View Paper
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