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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Antioxidants and Chenodeoxycholate

Research Papers that Mention the Interaction

Our results demonstrate that CDCA induces antioxidant and xenobiotic-metabolizing enzymes by activating C/EBPβ through AMPK-dependent ERK1/2 pathway downstream of FXR.
Drug Metabolism and Disposition  •  2011  |  View Paper
Further, the involvement of oxidative stress in cerebrotendinous xanthomatosis indicates that combined therapy with chenodeoxycholic acid and antioxidants may improve clinical outcome.
Redox report : communications in free radical research  •  2007  |  View Paper
Thus, we evaluated (a) the effects of bile acids (0–200 μmol L−… lymphocyte reduced glutathione content and malondialdehyde production and (b) the ability of antioxidants to prevent the … effect of chenodeoxycholic acid on interferon‐induced lymphocyte 2′,5′‐oligoadenylate synthetase …, an index of the biological activity of interferon.
European journal of clinical investigation  •  1997  |  View Paper
Metabolomic analysis showed that the metabolic processes responsible for antioxidant … disrupted by NET (e.g. upregulation of nervonyl carnitine and chenodeoxycholic acid 3-sulfate; downregulation of homolanthionine …) and these changes can undermine antioxidant defence by suppressing Nrf2-ARE and NF-κB pathways … to the synthesis of SOD and GSH.
Chemosphere  •  2021  |  View Paper