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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Antioxidants
drug:
Canagliflozin
Research Papers that Mention the Interaction
“In summary, we demonstrated that canagliflozin produces cardioprotective actions by promoting multiple antioxidant and anti-inflammatory signaling.”
“Our Western blotting and messenger RNA expression data demonstrated that canagliflozin augments antioxidant and anti-inflammatory signaling involving AMP-activated protein kinase (AMPK), Akt, endothelial nitric oxide synthase (eNOS), nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1).”
Canagliflozin attenuates isoprenaline-induced cardiac oxidative stress by stimulating multiple antioxidant and anti-inflammatory signaling pathways“Also, canagliflozin attenuated hepatic oxidative stress and elevated the antioxidant enzymes activity as well as the total antioxidant capacity.”
Canagliflozin protects against non‐alcoholic steatohepatitis in type‐2 diabetic rats through zinc alpha‐2 glycoprotein up‐regulation
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