supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Antioxidants
drug:
Bcg Vaccine
Research Papers that Mention the Interaction
“Supplementation with an antioxidant could enhance the antitumor effect of BCG.”
“Treating cells with BCG and the antioxidant N-acetylcysteine caused a greater reduction in reactive oxygen species, and induced earlier and greater cytotoxicity in MGH but not in RT112 cells.”
N-acetylcysteine augments the cellular redox changes and cytotoxic activity of internalized mycobacterium bovis in human bladder cancer cells.“Conclusions/Significance We conclude that antioxidants produced by BCG suppress host immune responses.”
“During decades of in vitro cultivation BCG not only lost some genes due to deletions of regions of the chromosome but also underwent gene duplication and other mutations resulting in increased antioxidant production.”
Reducing the Activity and Secretion of Microbial Antioxidants Enhances the Immunogenicity of BCG“It has been known that antioxidants enhance the antitumor effect of bacillus Calmette-Guerin (BCG), the most effective intravesical bladder cancer treatment.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback