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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
drug:
Apomorphine
Research Papers that Mention the Interaction
“Several agents already in therapeutic use might exert some of their effects by antioxidant action , including selegiline (deprenyl), apomorphine and nitecapone.”
Role of Free Radicals in the Neurodegenerative Diseases“Moreover, we found that the activation of the … induction of HO‐1 mRNA caused by Apo were suppressed … of the antioxidant N‐acetylcysteine and also that Apo produced intracellular reactive oxygen species (ROS), indicating that … level of ROS produced by Apo may play a critical role in this phenomenon.”
“The formation of protein carbonyls, which is generally less sensitive to antioxidants , could be significantly reduced by apomorphine.”
Apomorphine is a highly potent free radical scavenger in rat brain mitochondrial fraction.
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