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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Antioxidants and Antiparkinson Agents

Research Papers that Mention the Interaction

Recently, genetic and pharmacological accretion of the transcription factor, and phase II antioxidant ‘master regulator’ Nrf2, has shown to demonstrably mitigate the toxic neuronal effects of parkinsonian agents such as MPP+, rotenone, and hydrogen peroxide in vitro and in vivo.
Journal of Neural Transmission  •  2016  |  View Paper
5) Antioxidant defense mechanisms appear to be reduced in the parkinsonian substantia nigra with the findings of decreased activities of glutathione peroxidase and catalase. (
Annals of neurology  •  1992  |  View Paper
Conclusion: A higher level of dietary antioxidant nutrients may slow the rate of parkinsonian sign progression in older adults.
Nutritional neuroscience  •  2020  |  View Paper