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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Antioxidants
drug:
Aldesleukin
Research Papers that Mention the Interaction
“A drug regimen combining an NO stimulator (ISDN) with an antioxidant (hydralazine) favorably influences the nitroso-redox balance.”
BiDil (isosorbide dinitrate and hydralazine): a new fixed-dose combination of two older medications for the treatment of heart failure in black patients.“ Antioxidants decreased the serum sIL-2R in burned patients and attenuated the suppressive effect IL-2 production of normal human PBMC (P < 0.05 all).”
“NAC and some other thiol antioxidants have also been reported to regulate the activation of some transcription factors involved in IL-2 production, such as NFκB and activator protein-1 transcription factors [6].”
“We report here that all the anti-oxidants used suppressed T-lymphocyte proliferation and IL-2 synthesis, the former effect resulting very likely from the latter.”
Inhibition of murine T-cell responses by anti-oxidants: the targets of lipo-oxygenase pathway inhibitors.
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