supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Antimetabolites
supplement:
Thiamine
Research Papers that Mention the Interaction
“ Thiamine antimetabolites , in millimolar concentrations, reversibly decreased the maximum rate of rise and amplitude of the action potential while increasing its duration.”
Effects of thiamine antagonists on nerve conduction. I. Actions of antimetabolites and fern extract on propagated action potentials.“The action of the antimetabolite however was found to correlate with its ability to displace thiamine from the nerve.”
“Addition of an antimetabolite was advantageous in the thiamine and phenylalanine assays.”
ASSAY OF VITAMINS AND AMINO ACIDS WITH CULTURED TISSUE CELLS AND ANTIMETABOLITES.“Effective inhibition by the antimetabolite may be obtained at concentrations as low as 5.4 × 10−6 M. The inhibition can be overcome by adenine, adenosine, hypoxanthine, thiamine , or pyridoxine.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback