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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Antimetabolites and Thiamine

supplement:

Thiamine

Research Papers that Mention the Interaction

Thiamine antimetabolites , in millimolar concentrations, reversibly decreased the maximum rate of rise and amplitude of the action potential while increasing its duration.
Journal of neurobiology  •  1975  |  View Paper
The action of the antimetabolite however was found to correlate with its ability to displace thiamine from the nerve.
Biochimica et biophysica acta  •  1968  |  View Paper
Addition of an antimetabolite was advantageous in the thiamine and phenylalanine assays.
Applied microbiology  •  1964  |  View Paper
Effective inhibition by the antimetabolite may be obtained at concentrations as low as 5.4 × 10−6 M. The inhibition can be overcome by adenine, adenosine, hypoxanthine, thiamine , or pyridoxine.
Biochemical pharmacology  •  1962  |  View Paper