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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Antimalarials and Vitamin C

supplement:

Vitamin C

Research Papers that Mention the Interaction

Interpretation & conclusions: Co-incubation of blood with vitamin C and antimalarial combination drug potentiates the haemolytic effects of the latter on reducing blood viscosity and elasticity in vitro.
The elasticity of blood was significantly (P<0.05) reduced from 0.33 ± 0.04 mPa.s to 0.24 ± 0.03 mPa.s by the antimalarial drug , and further reduced to 0.13 ± 0.02 mPa.s in the presence of vitamin C (500 mg).
Vitamin C is associated with antioxidant properties which would be expected to protect against haemolytic effects of this antimalarial drug.
The Indian journal of medical research  •  2016  |  View Paper