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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Antimalarials
supplement:
Folic Acid
Research Papers that Mention the Interaction
“Folic acid reverses the inhibition by antifolate drugs of plasmodial growth or survival in vitro, and folic acid supplements given to children with malaria may increase the failure rate of treatment with antimalarials.”
Folic Acid Metabolism and Malaria“Anemia related to iron deficiency among children in subSaharan Africa has the same 20% prevalence as among pregnantwomen.6However, iron supplementation for children … screening tests) or have clinical symptoms of severe anemia.8 The recommendation also indicated that folic acid shouldnot beprovidedbecausesomeevidence,9albeitconflicting,7 suggests that folic … antifolatemalarial drugs.”
“The antimalarial activity of the diaminopyrimidines was partially in hibited by large oral doses of pteroylglutamic acid.”
“However, the possibility that antimalarial activity and other pharmacodynamic effects of WR 99,662 are exerted by inhibiting folic acid has not been ruled out.”
Cardiopulmonary effects of antimalarial drugs. V. Cycloguanil and a new triazine compound (WR 99,662).
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