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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Antimalarials
supplement:
Ascorbate
Research Papers that Mention the Interaction
“Since the antimalarial action of the drug is antagonised by glutathione and ascorbate and has unusual pharmacokinetic properties in humans, we have investigated if the drug is broken down by a typical reductive reaction in the presence of glutathione transferases.”
Proposed reductive metabolism of artemisinin by glutathione transferases in vitro
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