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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Antihypertensive Agents and Vitamin E

Research Papers that Mention the Interaction

Vitamin E supplementation increased the risk of subarachnoid hemorrhage (relative risk [RR], 2.45; 95% confidence interval [CI], 1.08-5.55) and decreased risk of cerebral infarction (RR, 0.70; 95% CI, 0.55-0.89) in hypertensive men but had no effect among normotensive men.
Archives of neurology  •  2000  |  View Paper
CONCLUSION Inclusion of vitamin E in antihypertensive therapy in post reperfusion hypertensive patients results in better management of blood pressure.
Experimental and clinical cardiology  •  2007  |  View Paper
These results supported our hypothesis and strongly suggested that the antithrombotic and antihypertensive effects of astaxanthin or vitamin E may be related to an increase in bioavailable NO, possibly mediated by decreased inactivation of NO by reactive oxygen species.
Nutrition research  •  2011  |  View Paper
Vitamin E lowers tissue aldehyde conjugates, cytosolic [Ca2+]i, and blood pressure in spontaneously hypertensive rats and fructose-induced hypertensive Wistar Kyoto rats, models of insulin resistance.
Journal of cardiovascular pharmacology and therapeutics  •  2005  |  View Paper
CONCLUSIONS These results indicate that very high alpha-tocopherol dietary amounts decrease cardiovascular risk in hypertensive rats with high oxidative stress, but have less effect on normotensive rats.
Medical science monitor : international medical journal of experimental and clinical research  •  2002  |  View Paper