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“On the contrary, methionine loading significantly increased plasma ET-1 levels only in hypertensives (P < 0.05), an effect which was not prevented by antioxidant vitamins (P < 0.05).”
“Results The genotypic frequency of the haplotype including both the 17 M and 235T alleles was higher among hypertensives than among normotensives (23 versus 14%, P = 0.02).”
“… M ) and disposal expressed as glucose sensitivity …) were significantly reduced in the hypertensives vs. controls (M: 6.8 +/- 0.9 vs. 9.7 +/- 0.8 mg/kg/min; MI: 7.1 +/- …. 12.5 +/- 1.7 mg/kg/min/mU/l x 100) (p = 0.03 and 0.01, respectively).”