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“Multiple evidences reveal that the rhythmicity of melatonin has a crucial role in a variety of cardiovascular pathophysiological processes including anti-inflammatory, antioxidant, anti-hypertensive and possibly as an antilipidemic function.”
Expert opinion on investigational drugs • 2012 | View Paper
“Role of rhythmicity of melatonin in anti-inflammatory, antioxidant, antihypertensive functions is currently under investigation and may offer an insight into the complex pathophysiological processes involved in CSX.”
International journal of cardiology • 2011 | View Paper
“Thus, an addition of melatonin 2 mg at night to stable antihypertensive treatment may improve nocturnal BP control in treated patients with nocturnal hypertension.”
The American journal of medicine • 2006 | View Paper
“We have demonstrated in a rat model of preeclampsia that melatonin exerts significant protective effects through lowering blood pressure and reducing oxidative stress.”