Possible Interaction: Antihypertensive Agents and Calcium Supplement

“ Antihypertensive treatment with a Ca2+ antagonist (nifedipine) induces early regression of such abnormalities with normalization of LV diastolic function.”

“The increments of urinary sodium and calcium and of plasma ANP, as well as the preinfusion plasma PTH level, were significantly (P less than .05) higher in hypertensives than in normotensives.”

“Combined calcium antagonism and beta-blockade may modify favourably surges in blood pressure and heart rate in ambulant hypertensives.”

“Magnesium and possibly also calcium supplements may be effective in reducing blood pressure in some hypertensives.”

“For instance, some antihypertensive drugs can affect epidermal differentiation by interfering with calcium or sodium channels in the skin.”

“Fifty-four (54) percent and twelve (12) percent of the hypertensives had reduced calcium and magnesium levels respectively, but none for the normotensive subjects.”

“Conclusions CACS >400 was associated with a higher likelihood of initiation and continuation of LLM, BPLM , and ASA.”

“Intima media thickness of the left (0.08 ± 0.01) and right (0.069 ± 0.008) CA were both significantly increased in hypertensives (p < 0.01).”

“According to hypertensive family history, the method of multiple variance analysis had been employed for 4 subgroups and the results revealed that the concentrations of serum Ca2+ and lymphocytic Na+ were significantly higher in hypertensives with or without family history than in normotensives without family history.”

“However, the response to caffeine was increased in vessels from the hypertensive patients, although the relationship between the dependence on the effect of calcium on the behaviour of arteries from hypertensives and controls was similar in the presence of prazosin and yohimbine.”