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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Antihemophilic Factor, Human Recombinant and Calcium Supplement

Research Papers that Mention the Interaction

FVIIa undergoes an active site transition upon binding TF in the presence of calcium which enhances the fundamental properties of the enzyme.
Bailliere's best practice & research. Clinical haematology  •  1999  |  View Paper
From the obtained results, it is concluded that GlycoPEGylation postpones the calcium induced thermal destabilisation of rFVIIa, and a much higher calcium concentration also postpones the thermally induced aggregation of rFVIIa.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V  •  2011  |  View Paper
Thus the presence of Ca eliminates the Mg-induced enhancement of FVIIa –TF amidolytic activity previously observed in its absence [7].
Journal of thrombosis and haemostasis : JTH  •  2007  |  View Paper
FVIIa undergoes an active site transition upon binding TF in the presence of calcium which enhances the fundamental properties of the enzyme.
Bailliere's clinical haematology  •  1994  |  View Paper
Increasing calcium ion concentrations result in decreased binding of recombinant human factor V and the mutant rHFV des-A3C1 to phosphatidylserine, similar to previous studies with purified plasma factor V and phospholipid vesicles.
The Journal of biological chemistry  •  1992  |  View Paper