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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Yohimbine
Research Papers that Mention the Interaction
“In depressed patients treated with tricyclic antidepressants (and exhibiting a reduced salivary flow), yohimbine also acutely increased salivary volume.”
Effect of 3 weeks treatment with yohimbine on salivary secretion in healthy volunteers and in depressed patients treated with tricyclic antidepressants.“In this test, a potential antidepressant should potentiate the behavioral and cardiovascular effects of yohimbine , a naturally occurring indole alkaloid, in conscious dogs.”
“In this test a potential antidepressant agent should potentiate the behavioral and cardiovascular effects of yohimbine , a naturally occurring indole alkaloid, in conscious dogs.”
“ Yohimbine given chronically for 3 weeks together with antidepressants counteracted the effect of imipramine and nortriptyline on behavioural despair.”
“In favor of this hypothesis, the reduction of beta binding sites is induced more rapidly after coadministration of alpha 2 receptor antagonist (such as yohimbine ) and antidepressant drugs.”
“Central nervous system depressants , amobarbital and Ro 5–0690, reduced the degree of response to yohimbine , whilst the CNS stimulants imipramine and epinephrine potentiated the yohimbine effect.”
“Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or … mix antidepressants and Panax ginseng; exacerbation of extrapyramidal effects with neuroleptic drugs and betel nut (Areca catechu); increased risk of hypertension when tricyclic antidepressants … yohimbine (….”
“ Yohimbine should be administered with caution to patients with high BP, especially in individuals with evidence for increased basal sympathetic outflow or those undergoing concurrent treatment with tricyclic antidepressants or other drugs that interfere with neuronal uptake or metabolism of NE.”
“It was investigated whether yohimbine , a primarily α2-receptor blocking agent, may have an antidepressant effect when given in addition to tricyclic antidepressants.”
“Co-administration of the α2-adrenoceptor antagonist yohimbine hastens the behavioral and neurogenic effects of the antidepressant imipramine.”
Hippocampal transcriptional and neurogenic changes evoked by combination yohimbine and imipramine treatment
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