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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Antidepressive Agents and S-Adenosylmethionine

Research Papers that Mention the Interaction

S-Adenosyl methionine may well have an antidepressant action beyond a placebo effect but this is virtually confined to endogenous depression.
Clinical neuropharmacology  •  1986  |  View Paper
Encouraging evidence exists for the use of omega-3 fatty acids, SAMe , folic acid and l-tryptophan adjuvantly with antidepressants to enhance response and improve efficacy.
Journal of psychiatric research  •  2010  |  View Paper
SAMe may have a faster onset of action than do conventional antidepressants and may potentiate the effect of tricyclic antidepressants.
The American journal of clinical nutrition  •  2002  |  View Paper
The monthly cost of SAMe , depending on the dose used, may be well over $200, exceeding that of most prescription antidepressants.
The Western journal of medicine  •  2000  |  View Paper