Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 years ago

Possible Interaction: Antidepressive Agents and S-Adenosylmethionine

Research Papers that Mention the Interaction

“ S-Adenosyl methionine may well have an antidepressant action beyond a placebo effect but this is virtually confined to endogenous depression.”
Clinical neuropharmacology  •  1986  |  View Paper
“Encouraging evidence exists for the use of omega-3 fatty acids, SAMe , folic acid and l-tryptophan adjuvantly with antidepressants to enhance response and improve efficacy.”
Journal of psychiatric research  •  2010  |  View Paper
“ SAMe may have a faster onset of action than do conventional antidepressants and may potentiate the effect of tricyclic antidepressants.”
The American journal of clinical nutrition  •  2002  |  View Paper
“The monthly cost of SAMe , depending on the dose used, may be well over $200, exceeding that of most prescription antidepressants.”
The Western journal of medicine  •  2000  |  View Paper