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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Antidepressive Agents and Polyunsaturated Fatty Acids

Research Papers that Mention the Interaction

Fish oil contains omega-3 polyunsaturated fatty acids (PUFA), and there are several mechanisms by which PUFAs are thought to induce an antidepressant effect , including anti-inflammatory action and direct effects on membrane properties.
Journal of integrative neuroscience  •  2017  |  View Paper
There is mounting evidence that low levels of some polyunsaturated fatty acids (PUFAs) play a role in the pathophysiology of depressive and aggressive disorders, including homicides.
Psychiatry Research  •  2003  |  View Paper
In parallel, PUFA also exerted antidepressant and neuroprotective activities, accompanied with neuroimmune-modulating actions.
Lipids in Health and Disease  •  2020  |  View Paper
The CREB-dependence and cAMP independence of this process suggests a manner in which n-3 PUFA could augment antidepressant effects.
Molecular Psychiatry  •  2020  |  View Paper