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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Polyunsaturated Fatty Acids
Research Papers that Mention the Interaction
“Fish oil contains omega-3 polyunsaturated fatty acids (PUFA), and there are several mechanisms by which PUFAs are thought to induce an antidepressant effect , including anti-inflammatory action and direct effects on membrane properties.”
Fish oil and depression: The skinny on fats.“There is mounting evidence that low levels of some polyunsaturated fatty acids (PUFAs) play a role in the pathophysiology of depressive and aggressive disorders, including homicides.”
“In parallel, PUFA also exerted antidepressant and neuroprotective activities, accompanied with neuroimmune-modulating actions.”
Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization“The CREB-dependence and cAMP independence of this process suggests a manner in which n-3 PUFA could augment antidepressant effects.”
N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells
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