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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium
Research Papers that Mention the Interaction
“The suppressant effect of antidepressants on Mg levels is probably a side effect of those drugs.”
Total and ionized calcium and magnesium are significantly lowered in drug-naïve depressed patients: effects of antidepressants and associations with immune activation“Patients who responded to antidepressant treatment showed higher Mg levels and higher retardation scores at basal evaluation in comparison with non-responders.”
“Also, enhancement of such activity by joint administration of magnesium and antidepressants was shown.”
NMDA/glutamate mechanism of antidepressant-like action of magnesium in forced swim test in mice“There is known to be an inverse relationship between concentration of magnesium and activity in marine species caused, perhaps, by the depressant action of magnesium at the neuromuscular junction1.”
“In order to reduce the risk of post-operative depression preoperatively, care should be taken when using magnesium combined with antidepressants and more studies are needed to be considered.”
Effects of Combined Sertraline and Magnesium in Rat Atrium.“In the literature there are reports concerning pharmacological studies in which a potentiation of the effects has been observed after a co-administration of antidepressant imipramine and magnesium.”
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