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“The addition of lithium carbonate to various antidepressant agents , including heterocyclics and monoamine oxidase inhibitors, has been reported to rapidly effect an antidepressant response in otherwise treatment-unresponsive depressed patients.”
Archives of general psychiatry • 1989 | View Paper
“To assess whether lithium carbonate augments antidepressant effects of long-term antidepressant treatment in non-responding patients, 15 treatment-refractory patients were studied using a placebo-controlled, double-blind design.”
“We concluded that lithium carbonate does augment the antidepressant effect when added to the long-term antidepressant treatment of nonresponding patients.”
Archives of general psychiatry • 1983 | View Paper
“The addition of lithium carbonate to an antidepressant drug regimen in depressed patients initially unresponsive to the antidepressants alone has been reported to bring about rapid improvement in the majority of these individuals.”