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Journal of Chemical Neuroanatomy • 2019 | View Paper
“As expected, CBD has been reported to interact with anti-epileptic drugs, antidepressants , opioid analgesics, and THC, but surprisingly, it interacts with several other common medications, e.g. acetaminophen, and substances including alcohol.”
Journal of General Internal Medicine • 2021 | View Paper
“Altogether, our results indicate that CBD regulates DNA methylation in brain regions relevant for depression neurobiology, suggesting that this mechanism could be related to CBD-induced antidepressant effects.”
“Conclusions Further pharmacokinetic examination of the interaction between CBD and citalopram/escitalopram is clearly warranted, and clinicians should be vigilant around the possibility of treatment-emergent adverse effects when CBD is introduced to patients taking these antidepressants.”