Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Antidepressive Agents and Arginine

Research Papers that Mention the Interaction

In Tricyclic antidepressant toxicity, R in aVR more than 3 mm is an adverse prognostic sign.
The Journal of the Association of Physicians of India  •  2013  |  View Paper
Objective We investigated whether the … oxide (NO) precursor, l-arginine , can prevent the antidepressant-… action of the fast-acting antidepressant , ketamine, in a genetic rat model of depression, and/or induce changes in the glutamate (Glu)/N-methyl-d-aspartate receptor (NMDAR)/NO/cyclic guanosine monophosphate (cGMP) signalling pathway.
Acta Neuropsychiatrica  •  2014  |  View Paper
Moreover, enhancement of NO synthesis by l-arginine reversed the effect of SSRI antidepressants , further demonstrating the role of NO in regulating the marble-burying behavior.
Neuroscience Letters  •  2010  |  View Paper
Thus, … antidepressants or antipsychotics could … metabolic pathway of arginine to yield urea or nitric oxide/nitrogen gas, increasing (if AP) or decreasing (if AD) urea or nitric oxide/nitrogen … and, secondarily, excitatory glutamic acid and/or inhibitory gamma aminobutyric acid levels via different pathways in the central nervous system.
Neuropsychiatric disease and treatment  •  2012  |  View Paper