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Last Updated: 2 years ago

Possible Interaction: Antidepressive Agents and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

Measurement of hormone concentrations revealed an enhanced release of adrenocorticotropic hormone and growth hormone in response to stress of hypoglycaemia in subjects treated with both antidepressants used.
Journal of psychopharmacology  •  2002  |  View Paper
Some antidepressant drugs , such as tianeptine, which were found to modulate ACTH release, appear to interfere with brain glutamatergic system.
Endocrine  •  2007  |  View Paper
Corticotropin (ACTH), but not cortisol, responses were blunted in depressives.
Biological Psychiatry  •  1986  |  View Paper
Depressive‐mice showed concomitant HPA axis dysregulation as observed from the significant increase in serum CORT and ACTH.
Behavioural Brain Research  •  2018  |  View Paper
Chronic daily administration of adrenocorticotropic hormone (ACTH) or corticosterone can alter behavioural responses to antidepressants , effectively blocking antidepressant efficacy.
Taken together these results indicate that pre-treatment with ACTH (100μg/day; 14 days) blocks the antidepressant effects of imipramine (10mg/kg), significantly alters key PFC monoamine responses to stress and downregulates glucocorticoid responses.
Behavioural Brain Research  •  2013  |  View Paper
Previous studies have shown that the antidepressive‐like effect of tricyclic antidepressants is blocked by repeated treatments with adrenocorticotropic hormone (ACTH).
Journal of biochemical and molecular toxicology  •  2013  |  View Paper
We have already reported that in rats, repeated adrenocorticotropic hormone (ACTH) treatment blocks the effect of tricyclic antidepressants in decreasing immobility time in a forced swim test, a widely used animal experiment for predicting antidepressant activity.
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology  •  2008  |  View Paper
We have already shown that the antidepressant-like effects of tricyclic antidepressants in the rat forced swim test (FST) are blocked by chronic treatment with adrenocorticotropic hormone (ACTH).
Pharmacology Biochemistry and Behavior  •  2008  |  View Paper
We have already shown that the antidepressant-like effects of tricyclic antidepressants in the rat forced swim test are blocked by repeated treatment with adrenocorticotropic hormone (ACTH).
European journal of pharmacology  •  2006  |  View Paper
Thus, ACTH seems to play a key role in decreasing the duration of immobility time of antidepressants in this test.
Life sciences  •  2001  |  View Paper
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