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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Anticonvulsants and Vitamin B 12

Research Papers that Mention the Interaction

It is recommended that both folic acid and vitamin B12 should be given as soon as a patient is started on anticonvulsant drugs to prevent mental deterioration.
British medical journal  •  1970  |  View Paper
Four cases are described of schizophrenia-like psychoses of epilepsy occurring in association with disturbances of folate and vitamin B12 metabolism induced by treatment with anticonvulsant drugs.
The British journal of psychiatry : the journal of mental science  •  1967  |  View Paper
It is possible either that anticonvulsants affect the absorption of vitamin B12 per se or that a deficiency of folic acid impairs vitamin-B12 absorption.
British medical journal  •  1966  |  View Paper
Data indicate that combinations of anticonvulsants with benfotiamine or cyanocobalamin are able to reduce tactile allodynia without affecting motor coordination in rats, and suggest the possible clinical use of these combinations in the treatment of neuropathic pain in humans.
Methods and findings in experimental and clinical pharmacology  •  2008  |  View Paper