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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Anticonvulsants
supplement:
Vitamin B 12
Research Papers that Mention the Interaction
“It is recommended that both folic acid and vitamin B12 should be given as soon as a patient is started on anticonvulsant drugs to prevent mental deterioration.”
Mental Deterioration in Epilepsy due to Folate Deficiency“Four cases are described of schizophrenia-like psychoses of epilepsy occurring in association with disturbances of folate and vitamin B12 metabolism induced by treatment with anticonvulsant drugs.”
“It is possible either that anticonvulsants affect the absorption of vitamin B12 per se or that a deficiency of folic acid impairs vitamin-B12 absorption.”
“Data indicate that combinations of anticonvulsants with benfotiamine or cyanocobalamin are able to reduce tactile allodynia without affecting motor coordination in rats, and suggest the possible clinical use of these combinations in the treatment of neuropathic pain in humans.”
Synergistic antiallodynic interaction between gabapentin or carbamazepine and either benfotiamine or cyanocobalamin in neuropathic rats.
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