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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Anticonvulsants
supplement:
Progesterone
Research Papers that Mention the Interaction
“Generally, estradiol has been shown to have activating effects, including the ability to increase seizure activity, while progesterone has been shown to have depressant effects, including anticonvulsant properties.”
Cellular and molecular effects of steroid hormones on CNS excitability.“These effects of progesterone may contribute to its anticonvulsant and anesthesia-related properties.”
Progesterone increases the activity of glutamate transporter type 3 expressed in Xenopus oocytes.“ Progesterone exerts anti-seizure effect against several chemoconvulsants.”
“ Progesterone induced significant anticonvulsive activity at moderate (50 mg/kg) and high (75 mg/kg) doses.”
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