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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Anticonvulsants
supplement:
Melatonin
Research Papers that Mention the Interaction
“The hormone melatonin has been shown to have significant anticonvulsant effects ; epileptic humans have lower serum melatonin levels than unaffected individuals.”
Serum Melatonin Values in Normal Dogs and Dogs with Seizures.“ Melatonin , at 40 and 80 mg/kg, and agmatine, at 10 and 20mg/kg, exerted anticonvulsant effects.”
“ Melatonin at the subconvulsive dose of 25 mg/kg potentiated the anticonvulsive activity of carbamazepine and phenobarbital (ED50 values were significantly decreased from 12.1 to 8.3 and from 18.9 to 11.8 mg/kg, respectively).”
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