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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Anticonvulsants
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“The ability of various anticonvulsant drugs to block the depolarization-induced [ Ca 2 + ] i transient of cultured astrocytes was assessed using the fluorescent probe indol.”
Pharmacological regulation of astrocytic calcium channels: implications for the treatment of seizure disorders.“ Anticonvulsants impair bone metabolism by induction of hepatic microsomal enzymes resulting in increased catabolism of 25(OH)vitamin D3 and perhaps also through inhibition of intestinal transport of calcium.”
“The results indicate a different effect of anticonvulsant drugs on calcium meta...”
“The 68 patients receiving combinations of anticonvulsants had the most marked reductions of calcium and phosphorus and increases of alkaline phosphatase.”
“Although the Ca2+ channel blocking actions of ifenprodil are observed at higher concentrations than those associated with NMDA antagonist activity, Ca2+ channel blockade may contribute, at least in part, to the established neuroprotective and anticonvulsant properties of the compound.”
Blockade by ifenprodil of high voltage‐activated Ca2+ channels in rat and mouse cultured hippocampal pyramidal neurones: comparison with N‐methyl‐D‐aspartate receptor antagonist actions“There is evidence to suggest that the anticonvulsant drugs affect the intestinal mechanism of active transport of calcium.”
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