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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Anticonvulsants
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“The mechanisms by which ACTH exerts anticonvulsant effects are unknown.”
ACTH Does Not Control Neonatal Seizures Induced by Administration of Exogenous Corticotropin‐Releasing Hormone“These results suggest that ACTH and its fragments may act as anticonvulsants by antagonizing glutamate binding, their interaction with GABA-A sites may relate to the other central nervous effects of ACTH than the anticonvulsant activity.”
Interactions of ACTH4–10 and ACTH1–24 with L-[3H] glutamate binding sites and GABA/benzodiazepine/picrotoxin receptor complexes in vitro
“The anticonvulsant effects of ACTH and melatonin are likely to involve regulation of the expression of these genes.”
The Instigation of the Associations Between Melatonin, Circadian Genes, and Epileptic Spasms in Infant Rats
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