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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“Administration of nonsteroid anti-inflammatory drugs AID ) inhibits hypotension and bronchoconstriction induced by the polyunsaturated prostaglandin (PG) precursor arachidonic acid (AA) and by slow reacting substance C (SRS-C, a mixture of unsaturated fatty acids split from lecithin by snake venom phospholipase A2).”
The pharmacology of slow reacting substance C and of arachidonic acid“However, n-3 PUFA supplementation significantly decreased NSAID requirements and leukotriene B4 levels in patients who weighed more than 55 kg.”
“Nonsteroidal anti-inflammatory drugs NSAIDs ) have demonstrated cancer chemoprevention effects associated with their ability to modulate polyunsaturated fatty acid metabolism.”
“ NSAIDs can alter the production of different metabolites of polyunsaturated fatty acids (linoleic and arachidonic acids) through effects on lipoxygenases (LOXs) and cyclooxygenases.”
“Administration of nonsteroid anti-inflammatory drugs AID ) inhibits hypotension and bronchoconstriction induced by the polyunsaturated prostaglandin (PG) precursor arachidonic acid (AA) and by slow reacting substance C (SRS-C, a mixture of unsaturated fatty acids split from lecithin by snake venom phospholipase A2).”
The pharmacology of slow reacting substance C and of arachidonic acid“Our study indicates that the gatekeeper function of ω-3 PUFAs improves GI safety when administered with NSAID.”
Mitigation of indomethacin-induced gastrointestinal damages in fat-1 transgenic mice via gate-keeper action of ω-3-polyunsaturated fatty acids
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