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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Long Chain Fatty Acid
Research Papers that Mention the Interaction
“We conclude that inhibition of long chain fatty acid oxidation via binding of NSAIDs to the alpha-subunit of the trifunctional protein may contribute to the inhibitory effects of NSAIDs on colorectal carcinoma cell growth.”
Binding of nonsteroidal antiinflammatory drugs to the alpha-subunit of the trifunctional protein of long chain fatty acid oxidation.“We conclude that the long chain fatty acid oxidation pathway may be a novel target for some of the inhibitory effects of NSAIDs on the growth of CRC cell lines.”
“We now report for the first time that NSAIDs inhibit oxidation of the long chain fatty acid palmitate in human CRC cell lines with potencies which are in good agreement with the potencies of NSAIDs as inhibitors of cell proliferation.”
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