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“The probability of having a symptom resolution by Day 3 or 4 with NSAID use is only less than three-fourths of that with antibiotic treatment (RR: 0.69, 95% CIs [0.55, 0.86], p = 0.0008, I 2 = 73%, moderate certainty of evidence).”
“ Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, phenylbutazone and oxyphenbutazone are known to potentiate ( I , 4, 5) and indomethacin and ibuprofen are known to antagonise the hypoglycaemic effect of oral sulphonylurea drugs (2).”