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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Anti-Inflammatory Agents, Non-Steroidal and Glutathione

Research Papers that Mention the Interaction

While inclusion of glutathione (GSH) in microsomal incubations resulted in a decrease in covalent binding for both NSAIDs , the reduction in binding was more pronounced for meloxicam.
Chemical research in toxicology  •  2008  |  View Paper
Among experimental circumstances both cysteine and glutathione , given in the same time as indomethacin or piroxicam, are capable to decrease the unwanted gastric side-effects of the non-steroidal anti-inflammatory drugs.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie  •  1997  |  View Paper
Liver GSH levels were lowered significantly by these anti-inflammatory drugs in rats with both types of inflammation and also in normal rats.
Biochemical pharmacology  •  1972  |  View Paper
Nonsteroidal anti-inflammatory drugs inhibit prostaglandin synthesis, which reduces the production of glutathione and renal perfusion.
Paediatrics & child health  •  2007  |  View Paper