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“Symptomatic slow acting drugs (avocado soybean unsaponifiable, chondroitin sulphate, diacerein, glucosamine sulphate ) have mild symptomatic effects and may reduce the consumption of NSAID.”
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke • 2010 | View Paper
“The possibility that combinations containing certain fixed ratios of glucosamine and certain nonsteroidal anti-inflammatory drugs (NSAIDs) might enhance pain relief in patients with pain or might achieve acceptable levels of pain relief with lower doses of NSAIDs (reduced adverse effects) is presently being pursued in clinical trials.”
Journal of Pharmacology and Experimental Therapeutics • 2003 | View Paper
“ Glucosamine reduces slightly the depression caused by NSAD , and this might be explained on the basis of consideration of the biochemical steps of MPS synthesis known to be inhibited by NSAD: glucosamine-GP-synthetase, acetyl-CoA-synthetase, and UDPG-dehydrogenase.”