Possible Interaction: Anti-Inflammatory Agents, Non-Steroidal and Cannabinoids

“Conclusions Some NSAIDs have additional influences on the cannabinoid system either by inhibiting fatty acid amide hydrolase (FAAH) or by inhibiting a possible intracellular transporter of endocannabinoids.”

“The authors perpetuate outdated information that nonsteroidal anti-inflammatory drugs (NSAIDs) can produce false-positive results for cannabinoids on the Syva EMIT and other immunoassay systems.”

“When compared with those not taking nabilone, patients using this cannabinoid had a lower rate of starting nonsteroidal anti-inflammatory agents , tricyclic antidepressants, gabapentin, dexamethasone, metoclopramide, and ondansetron and a greater tendency to discontinue these drugs.”

“In conclusion, combinations of low doses of cannabinoids and NSAIDs may be of interest from the therapeutic point of view.”

“The combination of cannabinoids and NSAIDs may have utility in the pharmacotherapy of pain.”

“Cannabinoids have been shown to increase the release of arachadonic acid, whereas nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the analgesic effects of cannabinoids.”

“Medications such as glucocorticoids, NSAIDs , topical capsaicin, and weak opioids are key elements when achieving analgesia in RA.Other pharmacological groups such as neuromodulators, antidepressants, muscle relaxants and cannabinoids currently do not have enough evidence to be recommended.”

“Cannabis and/or cannabinoids protect the gastric mucosa against noxious challenge with non-steroidal anti-inflammatory drugs , ethanol as well as against stress-induced mucosal damage.”