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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium
Research Papers that Mention the Interaction
“ Magnesium therapy may be useful in altering the proarrhythmic substrate in heart failure.”
Usefulness of magnesium sulfate in stabilizing cardiac repolarization in heart failure secondary to ischemic cardiomyopathy.“In the clinical setting high dose magnesium abolished torsade-de-pointes tachycardias caused by antiarrhythmic drugs.”
“The possible mechanism of the anti-arrhythmic influence of magnesium is briefly discussed.”
“These observations suggest a marked rate-dependent inhibitory observations suggest a marked rate-dependent inhibitory effect of magnesium on the refractoriness of the Hisbundle conduction and of the ventricular myocardium, which might be an important factor in the antiarrhythmic effectiveness of magnesium in ventricular tachyarrhythmias.”
The influence of elevated Mg2+ concentrations on cardiac electrophysiologic parameters“The suppressor effect of Mg on early afterdepolarisations and induced activity could, at least partially, explain its in vito antiarrhythmic action on torsades de pointe.”
“ Magnesium may possess intrinsic antiarrhythmic properties, and may potentially increase the efficacy of class III antiarrhythmics when used concomitantly.”
Efficacy of class III antiarrhythmics and magnesium combination therapy for atrial fibrillation
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