Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Anti-Arrhythmia Agents and Epinephrine

drug:

Anti-Arrhythmia Agents

supplement:

Epinephrine

Research Papers that Mention the Interaction

“ Arrhythmic dose of epinephrine and its plasma concentration in epidural lidocaine group were significantly higher than control (p<0.05).”
Epinephrine-induced arrhythmias: effects of thoracic epidural anesthesia and vagotomy during enflurane anesthesia in rabbits.
Journal of Korean medical science  •  1999  |  View Paper
“Patients at higher risk for serious adverse effects from epinephrine are those with comorbidities such as underlying heart disease and those taking monoamine oxidase inhibitors, tricyclic antidepressants, antiarrhythmics , and cocaine [8].”
High-sensitive troponin T levels and complex coronary lesions.
The American journal of emergency medicine  •  2013  |  View Paper
“Traditionally, perioperatively used inotropic agents, epinephrine , dobutamine, and milrinone, are limited by significant increases in myocardial oxygen consumption, proarrhythmia , or neurohormonal activation.”
Levosimendan in cardiac surgery: current best available evidence.
The Annals of thoracic surgery  •  2006  |  View Paper
“The meta bolic and hemodynamic changes during adrenaline infusion may not only reduce the antiarrhythmic efficacy of antiarrhythmics but may also increase the risk of proarrhythmic effects in a clinical setting.”
Metabolic, Hemodynamic, and Electrocardiographic Responses to Increased Circulating Adrenaline: Effects of Pretreatment with Class 1 Antiarrhythmics
Angiology  •  1991  |  View Paper
“Causes of the recovery of myocardial mechanical activity, effectuated by adrenaline or strophanthin in the presence of antiarrhythmic agents are discussed.”
[Effect of the anti-arrhythmia compounds etmozin and ethacizine on the contractile activity of myocardial preparations from heart defect patients].
Kardiologiia  •  1987  |  View Paper
“It has been suggested that in using such solutions the epinephrine per se counteracts, at least in part, the cardiac depression associated with local anesthetic toxicity (1-3).”
Cardiovascular collapse in an infant after caudal anesthesia with a lidocaine-epinephrine solution.
Anesthesia and analgesia  •  1986  |  View Paper
“Administered via the fourth ventricle, these two anti-arrhythmic agents also blocked the reflex vagal bradycardia induced by epinephrine or release of carotid artery occlusion.”
Effects of intracerebroventricular l-hyoscyamine, ethybenztropine and procaine on cardiac arrhythmias induced in dogs by pentylenetetrazol, picrotoxin or deslanoside.
International journal of neuropharmacology  •  1968  |  View Paper