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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Anthraquinones and Mitoxantrone

Research Papers that Mention the Interaction

Doxorubicin produced a maximal 3-fold enhancement of mitochondrial malondialdehyde production at 25 microM. The anthracenediones however, completely inhibited mitochondrial lipid peroxidation Drug-stimulated lipid peroxidation was also effectively diminished by mitoxantrone and ametantrone in a concentration-dependent manner.
The Journal of pharmacology and experimental therapeutics  •  1983  |  View Paper
Background Resistance to mitoxantrone (MTX), an anthracenedione antineoplastic agent used in advanced and metastatic androgen-refractory prostate cancer (PCa), seriously limits therapeutic success.
Cancer management and research  •  2019  |  View Paper