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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Anthraquinones
drug:
Mitoxantrone
Research Papers that Mention the Interaction
“Doxorubicin produced a maximal 3-fold enhancement of mitochondrial malondialdehyde production at 25 microM. The anthracenediones however, completely inhibited mitochondrial lipid peroxidation Drug-stimulated lipid peroxidation was also effectively diminished by mitoxantrone and ametantrone in a concentration-dependent manner.”
Inhibitory effects of anthracenedione antineoplastic agents on hepatic and cardiac lipid peroxidation.“Background Resistance to mitoxantrone (MTX), an anthracenedione antineoplastic agent used in advanced and metastatic androgen-refractory prostate cancer (PCa), seriously limits therapeutic success.”
Identification of key genes and specific pathways potentially involved in androgen-independent, mitoxantrone-resistant prostate cancer
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